Us epa, pesticide product label, thiophanatemethyl 50%. An interim assessment analysis of oncogenic dietary risk on the chemical thiophanate methyl. Hold eye open and rinse slowly and gently with water for 1520 minutes. In assessing the potential for additional sensitivity of infants and children to residues of thiophanate methyl and mbc, epa considered data from developmental toxicity studies in the rat and rabbit and a 2generation reproduction study in the rat. Index to pesticide chemical names, part 180 tolerance information, and food and feed commodities by commodity december 12, 2012. Do not use products containing f 1 thiabendazole or other products containing thiophanate wi. This iris summary has been removed from the iris database and is available for historical reference purposes. Based on the developmental and reproductive data on thiophanatemethyl and mbc, epa determined that an additional 3x safety factor for thiophanatemethyl and that an additional 10x safety factor for mbc for the protection of infants and children as required by fqpa should be retained. Nufarm thiophanatemethyl group 1 fungicide tmethyl 4. It does not include the maximum residue levels mrls that have been recommended by jmpr. Pesticide registration forms these forms are in pdf format and require the. Facts thiophanate methyl pesticide all pesticides sold or distributed in the united states must be registered by reregistration epa, based on scientific studies showing that they can be used without posing. Discontinue the use of thiophanate methyl 85 wdg for at least one season.
This fact sheet summarizes the information in the red document for reregistration case 2680, thiophanatemethyl tm and its primary metabolite carbendazim methyl 2 benzimidazole carbamate or mbc. Teratology study in rabbits with thiophanate methyl epa reg. Thiophanatemethyl per gallon keep out of reach of children caution see inside booklet for additional precautionary statements. Program and regulatory information about this substance, including links to epa applicationssystems, statuesregulations, or other sources that track or regulate this substance. It was determined that the acute and chronic dietary. These indexes are current as of the date indicated on this pdf. Us epa, pesticide product label, thiophanate methyl 4. Active ingredient frac brand name of fungicide active. To ensure proper receipt by epa, your objections and hearing requests must. Incompatible with strong oxidizing acids, peroxides. The amended label referred to above, submitted in connection with registration under the federal insecticide, fungicide and rodenticide act, as amended, is acceptable. A fungicide effective against a broad spectrum of diseases in fruit, vegetables, turf and other crops including eyespot, scab, powdery mildew and grey mould. Environmental protection and toxic substances november 2004.
In october 2005 the us epa published a red for thiophanatemethyl and its main metabolite carbendazim. This inventory summarizes evaluations of pesticides that have been performed by the joint faowho meeting on pesticide residues jmpr. Tm is a systemic fungicide used on a variety of tree, vine, and root crops. It is used as a broadspectrum systemic fungicide for agricultural use in australia. Pesticide registration forms these forms are in pdf format and require the acrobat. Thiophanate ethyl has extremely low toxicity to birds and moderate toxicity to fish and aquatic invertebrates. When a pesticide is eligible for reregistration, epa explains the basis for its decision in a reregistration eligibility decision red document. Manual manipulation of individual algal cells across with agar surface with a. Thiophanate methyl is incompatible with strong acids and bases, and with strong reducing agents such as hydrides. These indexes are current as of the date indicated in the pdf file. Specimen label thiophanate methyl 85%wdg revised date. Us epa pesticides index to pesticide chemical names, part. Produces flammable gaseous hydrogen with active metals or nitrides.
Since it targets a broad spectrum of diseases and plants, it has been used widely since 1973. Thiophanatemethyl tm thiophanatemethyl benzimidazole is a broadspectrum systemic fungicide that is absorbed by the roots and leaves of the treated plants. This regulation establishes timelimited tolerances for residues of thiophanate methyl and its metabolite methyl 2 benzimidazoyl carbamate mbc in or on citrus and blueberry. To avoid the development of tolerant or resist ant strains of fungi, topsin m 70wp should always be tankmixed with a fun gicide of different chemistry, andor a fungicide of different chemistry should. The fungicide methyl thiophanate widely used to control some of the most. Epa announced in a 2004 federal register notice that chemicals. United states prevention, pesticides october 2005 environmental protection and toxic substances agency 7508c pesticide reregistration use profile r. Any fungal population may contain individuals naturally resistant to this product and other group 1 fungicides. Thiophanatemethyl technical epa registration number. If after using topsin m wsb as recommended, and the treatment is not effective, a tolerant or resistant strain of fungi may be present. The listing of thiophanatemethyl was based upon three studies u. This iris assessment for thiophanatemethyl consists of hazard identification and doseresponse assessment data and provides support for epa risk management decisions. Thiophanatemethyl fungicide doityourself pest control. This iris assessment for thiophanate methyl consists of hazard identification and doseresponse assessment data and provides support for epa risk management decisions.
Thiophanatemethyl is a fungicide used on tree, vine, and root crops references. No later than one 1 day after the detained bags of thiophanate methyl technical and their contents if appropriate have been relabeled with the epa accepted label. Environmental protection agency national center for environmental assessment. Do not use products containing thiabendazole as substitutes for thiophanate methyl 85 wdg, as they are of. If you want more options, follow the instructions for category a on an epa chemicalresistance category selection chart.
An analysis of current thiophanate methyl uses, their benefits, the role of alternatives, impacts to agriculture from changes in thiophanate methyl use patterns, and applicator exposure 12 introduction 12 ornamentals 12 turfgrass diseases controlled by thiophanate methyl 14 dollar spot 14 brown patch 18. All pesticides sold or distributed in the united states must be registered by. Additional acute toxicity testing with channel catfish is being required because the chemically related compounds thiophanate methyl and benomyl are highly toxic to the ictalurid catfish family. Agricultural manual of requirements and guidelines. Human health assessment information on a chemical substance is included in the iris database. Thiophanate methyl is a low acute toxicity chemical.
If you want more options, follow the instructions for category c on an epa chemicalresistance selection chart. For crops without labeled uses of thiophanatemethyl, observe a 30day plantback restriction. This action is in response to epa s granting of emergency exemptions under section 18 of the federal insecticide. Thiophanate methyl may be applied as a dip treatment for rose budwood, nursery stock and cut flowers, or for potato pieces and peanuts as a seed treatment. The reconsideration of the active constituent thiophanatemethyl, registration of. For more information about the substance, you may click one of the links below to take you to the relevant section. Prenatal and postnatal sensitivity of thiophanate methyl. Us epa pesticides reregistration eligibility decision red for. Environmental protection and toxic substances november. Thiophanate methyl an overview sciencedirect topics. Facts thiophanate methyl all pesticides sold or distributed in the united states must be registered by epa, based on scientific studies showing that they can be used without posing. Thiophanate methyl is a member of the class of thioureas that is the dimethyl ester of 1,2phenylenedicarbamothioylbiscarbamic acid. Us epa pesticides fact sheet for thiophanatemethyl.
Pesticide residues in food food and agriculture organization of the. Agencys revised risk assessments for thiophanatemethyl, epa has identified risk. Details of the supplier of the safety data sheet manufacturer address. Us epa pesticides index to pesticide types and families. This iris summary has been removed from the iris database and. Systemic turf and ornamental fungicide for control of a broad spectrum of diseases of herbaceous, bedding, flowering and tropical foliage plants, shrubs, trees and flowers in the landscape, interiorscape, nursery and greenhouse, containerized woody shrubs and trees, and turfgrass. Specimen label thiophanatemethyl 85%wdg revised date. Thiophanate methyl is a broadspectrum fungicide used on food and feed. Thiophanate methyl has structural similarities to propylthiouracil, a known inducer of thyroid tumors in rats and mice. The most recent section 3 risk assessment performed for thiophanatemethyl was the hed.
Thiophanate methyl is rated high in hazard because it is classified as a likely human carcinogen and some of the potential exposures to children following lawn applications exceed the epa s level of concern. Environmental protection and toxic substances november 2004 agency 7508c r. Thiophanate methyl is a fungicide used on tree, vine, and root crops references. Thiophanatemethyl tm thiophanatemethyl fungicide label. If after using thiophanate methyl 85 wdg as recommended and the treatment is not effective, a tolerant or resistant strain of fungi may be present.
Biochemical aspects thiophanatemethyl is rapidly and almost completely absorbed 8889% after oral administration of a dose of 14 mgkg bw. Thiophanatemethyl is low in water solubility and is not expected to bind. Both this supplemental label and the full thiophanate methyl 4. Pesticide tolerance information is updated in the code of federal regulations on a weekly basis. As long as these precautions are followed, thiophanate methyl 4. Thiophanatemethyl is rapidly excreted approximately 47% in urine and approximately 40% in bile within 48 hours of administration. If after using thiophanate methyl 85 wdg as directed and the treatment is not effective, a tolerant or resistant strain of fungi may be present. Epas ecological risk assessment suggests that tm dose not pose a. Pesticide information about thiophanate methyl uc ipm.
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